signal.normexp {limma} | R Documentation

## Expected Signal Given Observed Foreground Under Normal+Exp Model

### Description

Adjust foreground intensities for observed background using Normal+Exp Model. This function is called by `backgroundCorrect` and is not normally called directly by the user.

### Usage

    signal.normexp(mu,sigma,alpha,foreground)

### Arguments

`mu` | numeric vector giving expected values for signal
`sigma` | numeric scalar giving standard deviation of background intensities
`alpha` | numeric scaler giving exponential decay rate of foreground intensities
`foreground` | numeric vector of foreground intensities

### Details

In general the vector `mu` is computed conditional on background at each spot.

### Value

Numeric vector containing adjusted intensities.

### Author(s)

Gordon Smyth

### See Also

`fit.normexp`

An overview of normalization and background correction functions is given in `4.Normalization`.

[Package limma version 1.9.6 Index]